Kuvumbura inyungu zinyuranye za dibenzocycloheptanone: reba neza ibyifuzo byayo

Mu rwego rwa chimie yubuvuzi, ibice bike bigaragara mubikorwa bitandukanye no gukora neza nka dibenzosuberone. Uru ruganda rudasanzwe, ruzwi kandi ku izina rya 1011-dihydrodibenzo [a, d] cyclohepten-5-imwe, rwashimishije abantu ku bushobozi bwo kuvura mu nzego zitandukanye z'ubuvuzi. Reka twibire cyane mwisi ya dibenzosuberone hanyuma dusuzume ibyiza byayo muguhinduka igice cyingenzi cyubuvuzi bugezweho.

Ku isonga ryubushakashatsi bwubuvuzi, dibenzosuberone yerekana imitungo yongerera agaciro cyane. Azwiho ubushobozi bwo gukora nka prodrug, bivuze ko ishobora guhinduka mubintu bya farumasi bikora mumubiri. Uyu mutungo udasanzwe ushoboza kuvura uburyo bwihariye bwo kuvura mugihe ugabanya ingaruka mbi, bigatuma uhitamo bwa mbere mugutezimbere ibiyobyabwenge.

Uburyo bwo kuvura bwa dibenzocycloconone buragutse cyane kandi buringaniye mubice byinshi byubuvuzi. Icy'ingenzi muri byo ni uruhare rwayo mu kuvura indwara zifata ubwonko. Ubushakashatsi bwerekana ko dibenzosuberone ishobora gufasha kugabanya ibimenyetso bifitanye isano n’indwara nka Parkinson, kandi ishobora gufasha mu kugenzura dopamine. Byongeye kandi, ubushakashatsi bwabwo bushobora kurwanya anticonvulsant, bwerekana ko bishoboka gukoreshwa mu kuvura igicuri.

Byongeye kandi, ingaruka zo kurwanya inflammatory ya dibenzosuberone zakozweho ubushakashatsi bwimbitse, byerekana ko ishobora gukoreshwa mu kuvura indwara zanduza. Kuva kuri rubagimpande kugeza indwara ziterwa na autoimmune, ubushobozi bwuru ruganda rwo guhindura ibisubizo byubudahangarwa bushobora gutera imbere mubuvuzi bukomeye.

Usibye ibi, dibenzosuberone nayo ikoresha muri endocrinology. Ubushobozi bwayo bwo gukorana na sisitemu ya hormone yumubiri byerekana ko igira uruhare mugutunganya inzira nka metabolism na homeostasis. Ibikorwa byinshi byerekana byinshi hamwe nakamaro ka dibenzosuberone muri chimie yimiti igezweho.

Inyungu za dibenzocycloconone zirenze ingaruka zo kuvura. Imiterere yimiti ihindurwa byoroshye, bituma abashakashatsi batezimbere ibikomoka hamwe nibikorwa byiza cyangwa ingaruka zigamije. Uku guhinduka mugushushanya no kubishyira mubikorwa bigira igikoresho cyagaciro cyo kuvumbura no gutera imbere.

Kubashaka dibenzocycloheptanone yo mu rwego rwo hejuru, Pharmaceutical ya Jingye itanga ibisubizo byizewe. Urubuga rwabo kurihttps://www.jingyepharma.com/dibenzosuberone-1011-dihydrodibenzoadcyclohepten-5-umuntu-byakozwe /itanga amakuru yuzuye kubyerekeye ibice byinshi. Imiti ya Jingye yiyemeje kuba indashyikirwa kandi ifite amateka yo gukora imiti yujuje ubuziranenge, ikwemeza ko ufite uburyo bworoshye kandi bwizewe bwo kugera kuri dibenzocycloheptanone.

Muri make, dibenzosuberone yerekana iterambere rishya mubumenyi bwa farumasi. Ubwinshi bwimikorere yabyo, kuva neurologiya kugeza endocrinology, hamwe nubushobozi bwayo bwo kuyitunganya yabigize urufatiro rwubuvuzi bugezweho. Mugihe dukomeje gushakisha ubujyakuzimu bwuru ruganda rudasanzwe, inyungu za dibenzosuberone ntagushidikanya ko zizagira ejo hazaza heza mubuvuzi.

SuraJingyeImiti ya farumasi uyumunsi kugirango umenye byinshi kubyerekeye intambwe imaze guterwa muri dibenzosuberone kandi wige uburyo iyi nteruro ishobora guhindura imyumvire yawe kubyerekeye udushya twa farumasi.