Ibikomoka kuri Benzophenone Byinshi Bikomoka kuri Pharmaceutical Porogaramu

Niki gituma ibikomoka kuri benzofenone bifite akamaro kanini mubikorwa bya farumasi? Niba warigeze wibaza uburyo ibintu bikora mubuvuzi bikozwe cyangwa uburyo reaction zimwe zigenzurwa muri laboratoire, ibikomoka kuri benzofenone bishobora kuba bimwe mubisubizo. Ibi bikoresho nibikoresho byingenzi muguhindura imiti no guteza imbere ibiyobyabwenge, bifasha kubaka molekile zigoye muburyo bwizewe kandi buhoraho.Tuzasuzuma ibikomoka kuri benzophenone aribyo, impamvu bifite akamaro, nuburyo Jingye Pharma itanga ubuziranenge binyuze mubikorwa bya GMP.

Ibikomoka kuri Benzophenone ni ibihe?

Ibikomoka kuri Benzophenone ni ibinyabuzima bishingiye ku miterere ya benzophenone, molekile ifite impeta ebyiri za benzene zifatanije nitsinda rya karubone hagati. Muguhindura iyi shingiro, abahanga mu bya shimi barashobora gukora ibintu byinshi byingirakamaro bigira uruhare runini mubuvuzi, kwisiga, hamwe nimiti myiza.

Mubikorwa bya farumasi, ibikomokaho bikoreshwa kenshi nka:

1.Ihuza muri synthesis yibikoresho bikora bya farumasi (APIs)

2.Fotoinitiator muri polymers yo murwego rwubuvuzi

3.Stabilisateur muri UV-yunvikana

Bitewe nuburyo bukora kandi butajegajega, ibikomoka kuri benzophenone bikora nkibice byingenzi byubaka muburyo bukomeye bwo guhuza ibinyabuzima.

Impamvu Ubuziranenge nuburyo butunganijwe muri Benzophenone

Iyo bigeze kuri synthesis ya chimique, ubuziranenge nibintu byose. Ndetse urwego rwimyanda irashobora kugira ingaruka kumikorere, umutekano, no gutuza kwibiyobyabwenge. Niyo mpamvu ibigo bikorerwamo ibya farumasi bishakisha ibikomoka kuri benzofenone bifite isuku ikozwe mu buryo bukomeye (GMP).

GMP iremeza ko buri ntambwe yumusaruro - gushakisha ibikoresho fatizo, kugenzura ibisubizo, kumisha, kuyungurura, no gupakira - gukurikiranwa neza no kwandika. Ibi ntibigabanya gusa ibyago byo kwanduzwa ahubwo binateza imbere icyiciro kimwe.

Urugero-rwukuri

Nk’uko ubushakashatsi bwasohotse mu kinyamakuru cyitwa Organic Process Research & Development (ACS Publications, 2020) bubitangaza, ikoreshwa ry’umuhuza wa benzophenone ufite isuku nyinshi mu guhuza intambwe nyinshi z’imiti igabanya ubukana bwa virusi byagabanije umwanda wose hejuru ya 40% kandi umusaruro wiyongereyeho 12%. Ibi birerekana uburyo ibintu byiza bishobora kugira ingaruka nziza kumutekano nibicuruzwa byanyuma.

Ibisubizo by'ingenzi mu kubyara Benzophenone

Kuri Jingye Pharma, ubuhanga bwacu buri muburyo bwiza bwo guhuza ibinyabuzima. Gukora ibikomoka kuri benzophenone neza kandi neza, turabisaba:

1.Hydrogenation reaction - kugabanya amatsinda ya karubone kugirango ahindurwe

2.Ubushyuhe bwo hejuru nubushyuhe buke - kubungabunga umutekano no kugenzura reaction

3.Grignard reaction - kubaka karubone-karubone ingirakamaro kumurongo wa benzophenone

4.Chlorination na okiside reaction - kumenyekanisha amatsinda akora kubikorwa wifuza

Buri reaction ikorwa hamwe no kugenzura cyane ubushyuhe, umuvuduko, hamwe nigisubizo kugirango ubuziranenge bwujuje ubuziranenge.

Gushyira mu bikorwa ibikomoka kuri Benzophenone muri Pharmaceuticals

Ihinduka ry’ibikomoka kuri benzophenone ibemerera guhuza uburyo butandukanye bwo gukoresha imiti, harimo:

1.Imiti igabanya ubukana

2.UV ikurura imiti ya dermal cyangwa amaso

3.Synthesis ihuza antihistamine, antipsychotics, nibiyobyabwenge birwanya inflammatory

Imiterere yimiti ituma ihinduka byoroshye, bigatuma bajya muri scafold muri gahunda ya chimie yimiti.

Kuki uhitamo Jingye Pharma kubikomoka kuri Benzophenone?

Muri Pharmaceutical ya Jiangsu Jingye, duhuza ikoranabuhanga rigezweho, ibikorwa byemewe na GMP, hamwe nubuhanga bwimbitse bwimiti kugirango tugemure ibikomoka kuri benzophenone byizewe kubakiriya bisi.

Dore icyadutandukanije:

1.Inganda zujuje ubuziranenge bwa GMP: Ibicuruzwa byose bikozwe mubikorwa byemewe byo gukora neza, byemeza ubuziranenge n'umutekano bihoraho.

2.

3. Kugenzura ubuziranenge bukomeye: Kuva mubikoresho fatizo kugeza kubipfunyika bwa nyuma, buri ntambwe ikurikiranwa binyuze mubikorwa byemewe hamwe ninyandiko zuzuye.

4. Ibicuruzwa bitandukanye: Urukurikirane rwa benzophenone rurimo ibintu byinshi bivamo guhuza inzira zitandukanye.

5. Itsinda ry'inararibonye: Hamwe na mirongo yuburambe bwa R&D hamwe nuburyo bwa mbere bwabakiriya, turatanga ibicuruzwa hamwe ninkunga yuzuye ya tekiniki.

Inshingano zacu zirasobanutse: Jingye Pharma, Kurinda Ubuzima binyuze mu Kwiyegurira Imana. Buri garama y'ibicuruzwa dukora byerekana iri sezerano.

Gutwara udushya hamwe nibikomoka kuri Benzophenone

Ibikomoka kuri Benzophenone ntibishobora kumenyekana cyane hanze ya laboratoire, ariko uruhare rwabo mubumenyi bwa farumasi ni ngombwa. Ibi bikoresho byinshi bifasha ibintu byose uhereye kumurongo mwiza wo hagati ukageza kumiti itekanye, yizewe.

Kuri Pharmaceutical ya Jingye, ntabwo dutanga gusaibikomoka kuri benzophenone- turabashiraho ubuhanga, ubuziranenge, nibikorwa. Dushyigikiwe ninganda zemewe na GMP, ubuhanga buhanitse bwa synthesis, hamwe na sisitemu yubuziranenge, ibicuruzwa byacu byizewe nabashya ba farumasi kwisi.

Mugihe dukomeje kwagura urutonde rwa benzophenone no kunonosora inzira zacu, Jingye akomeza kwiyemeza gufasha abakiriya gufungura chimie igoye bafite ikizere. Urusange rumwe icyarimwe, twubaka ejo hazaza heza, hatekanye binyuze mubumenyi.